ChemicalBook--->CAS DataBase List--->63762-74-3

63762-74-3

63762-74-3 Structure

63762-74-3 Structure
IdentificationBack Directory
[Name]

6-CHLOROMELATONIN
[CAS]

63762-74-3
[Synonyms]

6-CHLOROMELATONIN
Melatonin Impurity 8
Melatonin 6-Chloro Impurity
N-Acetyl-6-chloro-5-methoxytryptamine
N-[2-(6-CHLORO-5-METHOXYINDOL-3-YL)ETHYL]ACETAMIDE
N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)ethyl]acetamide
n-(2-(6-chloro-5-methoxy-1h-indol-3-yl)ethyl)-acetamid
Acetamide, N-[2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl]-
[Molecular Formula]

C13H15ClN2O2
[MDL Number]

MFCD00209923
[MOL File]

63762-74-3.mol
[Molecular Weight]

266.72
Chemical PropertiesBack Directory
[Melting point ]

147-148 °C
[Boiling point ]

536.7±50.0 °C(Predicted)
[density ]

1.272±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

alcohol: soluble
[form ]

Powder
[pka]

15.99±0.30(Predicted)
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

60-23/24/25-36/37/38
[Safety Statements ]

53-26-36/37/39-45
[WGK Germany ]

3
[RTECS ]

AB5750000
Hazard InformationBack Directory
[Uses]

6-Chloromelatonin is a potent agonist of the melatonin receptors.
[Definition]

ChEBI: N-[2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl]acetamide is a member of acetamides.
[Biological Activity]

Potent melatonin agonist (pK i values are 9.10 and 9.77 for human recombinant MT 1 and MT 2 receptors respectively). Displays higher affinity for binding to hamster brain membrane and chicken retina than melatonin.
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