ChemicalBook--->CAS DataBase List--->64315-16-8

64315-16-8

64315-16-8 Structure

64315-16-8 Structure
IdentificationBack Directory
[Name]

ANGIOTENSINOGEN
[CAS]

64315-16-8
[Synonyms]

RENIN SUBSTRATE
ANGIOTENSINOGEN
Angiotensinogen/CH8530
ANGIOTENSINOGEN (1-14) (HORSE)
ANGIOTENSINOGEN (1-14), PORCINE
angiotensinogen from hog plasma
Tetradecapeptide renin substrate
PREANGIOTENSINOGEN (1-14) (HORSE)
Hypertensinogen (tetradecapeptide)
ANGIOTENSINOGEN FROM PORCINE PLASMA
ANGIOTENSINOGEN FRAGMENT 1-14 PORCINE
ANGIOTENSINOGEN FROM HOG PLASMA, ~2 U/MG
RENIN SUBSTRATE TETRADECAPEPTIDE PORCINE
TETRADECAPEPTIDE RENIN SUBSTRATE (HORSE)
Angiotensinogen (tetradecapeptide renin substrate)
ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER
H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH
Angiotensinogen from hog plasma, Hypertensinogen, Renin substrate
[Molecular Formula]

C85H123N21O20
[MDL Number]

MFCD00133798
[MOL File]

64315-16-8.mol
[Molecular Weight]

1759.01
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

H2O: 0.3 mg/mL, clear, colorless
[form ]

lyophilized powder
Safety DataBack Directory
[WGK Germany ]

3
[F ]

10-21
Hazard InformationBack Directory
[Purification Methods]

This rennin substrate is purified 390-fold from the serum by chromatography on Blue Sepharose, phenyl sepharose, hydroxyapatite and finally by affinity chromatography on 5-hydroxytryptamine (5-HT) sepharose to which it specifically binds to the 5-HT. It is applied to the latter column in 50mM sodium phosphate at pH 7 and after washing, it is eluted by increasing the ionic strength with 100mM sodium phosphate buffer containing 250mM NaCl. The multiple forms are separated by SDSPAGE and have pI 4.40-4.82. [Campbell et al. Biochem J 243 121 1987.]
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