| Identification | Back Directory | [Name]
Bouvardin | [CAS]
64755-14-2 | [Synonyms]
Bouvardin
Cyclo[D-alanyl-L-alanyl-N,O-dimethyl-L-tyrosyl-L-alanyl-(βS)-β-hydroxy-N-methyl-L-tyrosyl-3-hydroxy-N-methyl-L-tyrosyl], cyclic (54→63)-ether | [Molecular Formula]
C40H48N6O10 | [MDL Number]
MFCD01740786 | [MOL File]
64755-14-2.mol | [Molecular Weight]
772.84 |
| Chemical Properties | Back Directory | [Boiling point ]
738.17°C (rough estimate) | [density ]
1.2175 (rough estimate) | [refractive index ]
1.6400 (estimate) | [pka]
9.07±0.70(Predicted) |
| Hazard Information | Back Directory | [Enzyme inhibitor]
This cyclic hexapeptide antitumor agent (FW = 772.86 g/mol; CAS 64755- 14-2), from Bouvardia ternifolia (scarlet bourvardia or trumpetilla), also known as NSC 259968, inhibits protein synthesis in intact eukaryotic cells and cell-free systems. Bouvardin inhibits EF1-dependent binding of aminoacyl-tRNA and EF2-dependent translocation of peptidyl-tRNA but does not affect the nonenzymic translocation since this reaction does not require EF2. Bouvardin contains L- and D-alanine, and N-methyl-L-tyrosine. |
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| Company Name: |
Alabiotech Inc.
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| Tel: |
001-619-354-5251 |
| Website: |
www.alabiotech-e.com |
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