ChemicalBook--->CAS DataBase List--->64821-19-8

64821-19-8

64821-19-8 Structure

64821-19-8 Structure
IdentificationBack Directory
[Name]

VAR10300 dihydrochloride
[CAS]

64821-19-8
[Synonyms]

M30 dihydrochloride
M-30 dihydrochloride
VAR10300 dihydrochloride
MAO-IN-M30 dihydrochloride
5-[[Methyl(2-propyn-1-yl)amino]methyl]-8-quinolinol Dihydrochloride
5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride
N-(8-Hydroxy-5-quinolylmethyl)-N-methyl-2-propynylamine dihydrochloride
[Molecular Formula]

C14H16Cl2N2O
[MDL Number]

MFCD20488063
[MOL File]

64821-19-8.mol
[Molecular Weight]

299.196
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO, heptane and xylene: ≥21mg/mL
[form ]

powder
[color ]

green-yellow
[Water Solubility ]

Soluble to 100 mM in water
Safety DataBack Directory
[Symbol(GHS) ]


GHS05,GHS07
[Signal word ]

Danger
[Hazard statements ]

H302-H318
[Precautionary statements ]

P280-P301+P312+P330-P305+P351+P338+P310
[Hazard Codes ]

Xn
[Risk Statements ]

22-41
[Safety Statements ]

26-39
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

M 30 Dihydrochloride is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA (Cat. No. 2547) induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson''s disease model.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

VAR10300 dihydrochloride(64821-19-8)1HNMR
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