| Identification | Back Directory | [Name]
TYR-D-ALA-GLY-PHE-LEU | [CAS]
64963-01-5 | [Synonyms]
TYR-D-ALA-GLY-PHE-LEU
D-ALA2-LEU5-ENKEPHALIN
(D-Ala)-Leu-Enkephalin
(D-ALA2)-LEU-ENKEPHALIN
Pentapeptide-3/Leuphasyl
Tyr-D-Ala-Gly-Phe-Leu-OH
H-TYR-D-ALA-GLY-PHE-LEU-OH
Leuphasyl / Pentapeptide-3
Leuphasyl / Pentapeptide-18
[D-ALA2]-LEUCINE ENKEPHALIN
(D-alanine2)leucine enkephalin
L-Tyr-D-Ala-Gly-L-Phe-L-Leu-OH
TYR-D-ALA-GLY-PHE-LEU USP/EP/BP
[D-ALA2]LEUCINE-ENKEPHALIN, >99%
Tyrosyl-D-alanylglycylphenylalanylleucine
[D-Ala2]-Leucine enkephalin,Tyr-D-Ala-Gly-Phe-Leu
L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-L-leucine
(D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH
Pentapeptide-18/Leuphasyl with reduce facial muscle
L-Leucine, L-tyrosyl-D-alanylglycyl-L-phenylalanyl-
[D-Ala2]leucine-enkephalin,Tyr-D-Ala-Gly-Phe-Leu, >99%
N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-L-leucine
Lab Supply High Purity Pentapeptide-18 Powder CAS 64963-01-5 with Best Price
2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoicaci
2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenyl-propanoyl]amino]-4-methyl-valeric acid
2-[[2-[2-[2-[[2-azanyl-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid | [EINECS(EC#)]
265-291-0 | [Molecular Formula]
C29H39N5O7 | [MDL Number]
MFCD00076409 | [MOL File]
64963-01-5.mol | [Molecular Weight]
569.65 |
| Chemical Properties | Back Directory | [Melting point ]
160-163.5 °C | [Boiling point ]
991.9±65.0 °C(Predicted) | [density ]
1.257±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMF (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
3.40±0.10(Predicted) | [color ]
White to Off-White | [InChIKey]
ZHUJMSMQIPIPTF-JMBSJVKXSA-N | [SMILES]
C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)N |
| Hazard Information | Back Directory | [Definition]
The leucine-enkephalin (Tyr-Gly-Gly-Phe-Leu, Leu-enk) is a natural endogenous ligand for opiate receptors. Leu-enk is rapidly metabolized in vivo and in vitro[1]. (D-Ala2)-Leu-Enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin.
| [benefits]
(D-Ala2)-Leu-Enkephalin is widely distributed in the human body and has essential physiological functions. It has a unique effect on brain cells and can activate sleeping brain cells and have a good recovery effect on the sequelae caused by brain damage. It plays an important role in immune function, including increasing the activity of the immune system, T lymphocytes, NK cells, macrophages, antiviral, and the release of gamma interferon. It can participate in immune regulation by promoting the secretion of endocrine cells by activated immune cells, thereby affecting DNA's gene regulation and expression functions.
| [storage]
Store at -20°C | [References]
[1] H. Hasegawa, S. Baba, Y. Shinohara. “Synthesis of [D-Ala2]Leu-enkephalin and [D-Ala2, D-Leu5]Leu-enkephalin with high specific tritiated activity in the leucine residue.” Journal of The Chemical Society-perkin Transactions 1 12 1 (1990): 2641–2644.
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