| Identification | More | [Name]
Cefotiam hydrochloride | [CAS]
66309-69-1 | [Synonyms]
(6r-trans)-7-[2-(2-aminothiazol-4-yl)acetamido]-3-[[[1-[2-(dimethylamino)ethyl]-1h-tetrazol-5-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
CEFOTIAM
CEFOTIAM 2HCL
cefotiam hydrochloride
cefotiamdihydrochloride
dihydrochloride,(6r-trans)--oxo
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, dihydrochloride, (6R,7R)-
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, dihydrochloride, (6R-trans)-
Abbott 48999
Halospor
Pansporin
Pansporine
Spizef
Sporidyn
(6R-trans)-7-[2-(2-aminothiazol-4-yl)acetamido]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
Cefapicol
Kemisporin
Sepidnarin | [EINECS(EC#)]
266-312-6 | [Molecular Formula]
C18H23N9O4S3 | [MDL Number]
MFCD00865087 | [Molecular Weight]
525.63 | [MOL File]
66309-69-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
>93°C (dec.) | [Boiling point ]
94℃ | [RTECS ]
XI0367000 | [Fp ]
>110°(230°F) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
H2O: ≥22M | [form ]
powder | [color ]
white to tan | [Water Solubility ]
Soluble in water | [Stability:]
Hygroscopic | [InChIKey]
BWRRTAXZCKVRON-DGPOFWGLSA-N | [CAS DataBase Reference]
66309-69-1(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
A broad spectrum antibiotic | [Uses]
antiprotozoal, trypanocidal, antiviral | [Uses]
Cephalosporin Antibiotic. | [Definition]
ChEBI: The dihydrochloride salt of cefotiam. | [Brand name]
Ceradon (Takeda). | [Pharmacokinetics]
Cefotiam Hydrochloride is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted. |
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