| Identification | Back Directory | [Name]
Arterolane | [CAS]
664338-39-0 | [Synonyms]
OZ 277
RBx 11160)
Arterolane
Arterolane
(OZ277
-[1,2,4]trioxolane-5&rsquo
-tricyclo[3.3.1.13,7]decane]-4-acetamide
cis-N-(2-Amino-2-methylpropyl)dispiro[cyclohexane-1,3&rsquo
Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decane]-4-acetamide, N-(2-amino-2-methylpropyl)-, cis- | [Molecular Formula]
C22H36N2O4 | [MOL File]
664338-39-0.mol | [Molecular Weight]
392.53 |
| Chemical Properties | Back Directory | [Melting point ]
160-162℃ | [Boiling point ]
572.2±45.0 °C(Predicted) | [density ]
1.20 | [storage temp. ]
Store at -20°C, protect from light, stored under nitrogen | [solubility ]
DMSO: soluble | [form ]
A solid | [pka]
16.70±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Definition]
ChEBI: Arterolane is an oxaspiro compound that is dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.1(3,7)]decane] substituted by a 2-[(2-amino-2-methylpropyl)amino]-2-oxoethyl group at position 4s. Its maleic acid salt is used as an antimalarial drug in combination with piperaquine. It has a role as an antimalarial and an antiplasmodial drug. It is a member of adamantanes, a secondary carboxamide, a primary amino compound, a trioxolane and an oxaspiro compound. It is a conjugate base of an arterolane(1+). | [storage]
Store at -20°C, protect from light, stored under nitrogen |
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| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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