| Identification | Back Directory | [Name]
2-azaspiro[3.3]heptane | [CAS]
665-04-3 | [Synonyms]
2-azaspiro[3.3]heptane
2-Azaspiro[3.3]heptane-HCl
2-azaspiro[3.3]heptane oxalate
2-Azaspiro[3.3]heptane hydrochloride | [Molecular Formula]
C6H11N | [MDL Number]
MFCD11186837 | [MOL File]
665-04-3.mol | [Molecular Weight]
97.16 |
| Hazard Information | Back Directory | [Synthesis]
2-tosyl-2-azaspiro[3.3]heptanes (7.3g, 0.03mol) was dissolved in 30mL 1,2-dimethoxyethane. To the resulting mixture was added dropwise 50mL of a fresh-made sodium naphthalene solution under cooling in ice-water. The resulting mixture was reacted at room temperature for 1h. The reaction was quenched with water. The reaction liquor was concentrated and then purified with a silica-gel column (dichlormethane:methanol=20: 0-1: 0) to produce 2.41g 2-azaspiro[3.3]heptane in a yield of 83%. |
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