| Identification | Back Directory | [Name]
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine | [CAS]
681482-80-4 | [Synonyms]
1-[4-(oxan-2-yloxy)phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine
Piperidine, 1-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]- | [Molecular Formula]
C23H26F3NO4 | [MOL File]
681482-80-4.mol | [Molecular Weight]
437.45 |
| Chemical Properties | Back Directory | [Boiling point ]
530.2±50.0 °C(Predicted) | [density ]
1.252±0.06 g/cm3(Predicted) | [solubility ]
soluble in Chloroform, DCM | [form ]
Solid | [pka]
3.84±0.20(Predicted) | [color ]
Off-White |
| Hazard Information | Back Directory | [Uses]
1-[4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. |
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