| Identification | Back Directory | [Name]
(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole | [CAS]
681490-91-5 | [Synonyms]
Delamanid Diol Impurity
Deflazacort Impurity 14
(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole
1,2-Propanediol, 3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-, (2R)- | [Molecular Formula]
C7H10ClN3O4 | [MDL Number]
MFCD30741734 | [MOL File]
681490-91-5.mol | [Molecular Weight]
235.62 |
| Chemical Properties | Back Directory | [Boiling point ]
515.1±60.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3(Predicted) | [solubility ]
soluble in Chloroform, DCM | [form ]
Solid | [pka]
13.48±0.29(Predicted) | [color ]
Off-White |
| Hazard Information | Back Directory | [Uses]
(2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. |
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