| Identification | Back Directory | [Name]
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole | [CAS]
681490-95-9 | [Synonyms]
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate
1H-Imidazole-1-propanol, 2-chloro-β-hydroxy-β-methyl-4-nitro-, 1-(4-nitrobenzoate), (βR)- | [Molecular Formula]
C14H13ClN4O7 | [MOL File]
681490-95-9.mol | [Molecular Weight]
384.73 |
| Chemical Properties | Back Directory | [Melting point ]
122-123 °C(Solv: ethyl acetate (141-78-6); isopropyl ether (108-20-3)) | [Boiling point ]
638.9±65.0 °C(Predicted) | [density ]
1.58±0.1 g/cm3(Predicted) | [solubility ]
Chloroform, DCM | [form ]
Solid | [pka]
12.81±0.29(Predicted) | [color ]
Off-White |
| Hazard Information | Back Directory | [Uses]
(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. |
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