| Identification | Back Directory | [Name]
N,N-DIMETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE | [CAS]
68192-15-4 | [Synonyms]
Prostaglandin F2α dimethyl amide
Prostaglandin F2α dimethyl amide
PROSTAGLANDIN F2ALPHA DIMETHYL AMIDE
N,N-DIMETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE
Prosta-5,13-dien-1-amide, 9,11,15-trihydroxy-N,N-dimethyl-, (5Z,9α,11α,13E,15R)- (9CI) | [Molecular Formula]
C22H39NO4 | [MDL Number]
MFCD00797652 | [MOL File]
68192-15-4.mol | [Molecular Weight]
381.55 |
| Chemical Properties | Back Directory | [solubility ]
DMF: >50 mg/ml (from PGF2a dimethyl; DMSO: >50 mg/ml (from PGF2a dimethyl; Ethanol: >20 mg/ml (from PGF2a dimethyl; Methyl Acetate: >10 mg/ml (from PGF2a dimethyl; PBS pH 7.2: >3 mg/ml (from PGF2a dimethyl |
| Hazard Information | Back Directory | [Description]
Prostaglandin F2α (PGF2α) dimethyl amide is a weak FP receptor antagonist.1 In gerbil colon, PGF2α dimethyl amide at a dose of 3.2 μg/ml inhibits the contractile effects of PGF2α (at 6 ng/ml) by 50%.1 | [References]
1. Maddox, Y.T., Ramwell, P.T., Shiner, C.S., et al. Amide and l-amino derivatives of F prostaglandins as prostaglandin antagonists Nature 273,549-552(1978). |
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