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68324-96-9

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68324-96-9 Structure

68324-96-9 Structure
IdentificationBack Directory
[Name]

6,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID, SODIUM SALT
[CAS]

68324-96-9
[Synonyms]

Prostaglandin I3 (sodium)
JYCZBBNTGSRZMY-YICKWJRGSA-M
PROSTAGLANDIN I3 SODIUM SALT
Prostaglandin I3 (sodium salt) Exclusive
6,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID, SODIUM SALT
[Molecular Formula]

C20H29NaO5
[MDL Number]

MFCD00216080
[MOL File]

68324-96-9.mol
[Molecular Weight]

372.43
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

PBS (pH >10.2): 10 mg/ml
[form ]

A lyophilized powder
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P321-P330-P362+P364-P501
Hazard InformationBack Directory
[Description]

PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to Δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.1,2
[References]

1. Mann, N.J., Warrick, G.E., O'Dea, K., et al. The effect of linoleic, arachidonic, and eicosapentaenoic acid supplementation of prostacyclin production in rats Lipids 29(3),157-162(1994).
2. Johnson, R.A., Lincoln, F.H., Nidy, E.G., et al. Synthesis and characterization of prostacyclin, 6-ketoprostaglandin F1α, prostaglandin I1, and prostaglandin I3 J. Am. Chem. Soc. 100(24),7690-7704(1978).
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