| Identification | Back Directory | [Name]
CAY10464 | [CAS]
688348-37-0 | [Synonyms]
CAY10464
CAY10464 Exclusive
1,3-dichloro-5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene
1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene
Benzene, 1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]- | [Molecular Formula]
C15H12Cl2O | [MDL Number]
MFCD08457907 | [MOL File]
688348-37-0.mol | [Molecular Weight]
279.16 |
| Chemical Properties | Back Directory | [Boiling point ]
409.3±45.0 °C(Predicted) | [density ]
1.265±0.06 g/cm3(Predicted) | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:1): .5 mg/ml; Ethanol: 10 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin (TCDD, 2,3,7,8-tetrachlorodibenzoparadioxin), benzo[a]pyrene, and numerous polyaromatic hydrocarbons from soot particles and coal tar. CAY10464 is a potent and selective AhR antagonist, with a Ki of 1.4 nM when tested in rabbit liver cytosol preparations. It is inactive as an estrogen receptor ligands even at 100 μM. |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Resenbio
|
| Tel: |
029-86354885 |
| Website: |
www.xarxbio.com |
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