| Identification | Back Directory | [Name]
2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE | [CAS]
6890-08-0 | [Synonyms]
2-hydroxy-4h-isoquinoline-1,3-dione
2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE
2-HYDROXY-1,3(2H,4H)-ISOQUINOLINEDIONE
1,3(2H,4H)-Isoquinolinedione, 2-hydroxy-
2-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1,3-dione | [Molecular Formula]
C9H7NO3 | [MDL Number]
MFCD00835191 | [MOL File]
6890-08-0.mol | [Molecular Weight]
177.16 |
| Chemical Properties | Back Directory | [Melting point ]
197-200°C | [Boiling point ]
382.7±45.0 °C(Predicted) | [density ]
1.510±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
7.65±0.20(Predicted) | [color ]
Pale Beige to Brown |
| Hazard Information | Back Directory | [Chemical Properties]
Brown Solid | [Uses]
2-Hydroxyisoquinoline-1,3(2H,4H)-dione was recently discovered as a scaffold for the inhibition of HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase. Its interaction with Mg2+ and Mn2+ was investigated using different spectroscopic techniques and it was reported that 2-hydroxyisoquinoline-1,3(2H,4H)-dione forms a 1:1 complex with Mg2+ but a 1:2 complex with Mn2+. Antiviral agent. |
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