| Identification | Back Directory | [Name]
EG1
(Pax2 inhibitor EG1) | [CAS]
693241-54-2 | [Synonyms]
Pax2 inhibitor EG1
EG1
(Pax2 inhibitor EG1)
Benzoic acid, 2-[[4-[(2-methoxybenzoyl)amino]benzoyl]amino]- | [Molecular Formula]
C22H18N2O5 | [MOL File]
693241-54-2.mol | [Molecular Weight]
390.39 |
| Chemical Properties | Back Directory | [Boiling point ]
490.9±40.0 °C(Predicted) | [density ]
1.376±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 83.33 mg/mL (213.45 mM; Need ultrasonic) | [form ]
Solid | [pka]
3.44±0.36(Predicted) | [color ]
Off-white to yellow |
| Hazard Information | Back Directory | [Uses]
EG1, a specific Pax2 inhibitor, directly binds the paired domain of Pax2 (Kd=1.35-1.5 μM) and inhibits Pax2-DNA interactions. EG1 can inhibit embryonic kidney development, a process directly dependent on Pax2 activity[1]. | [storage]
Store at -20°C | [References]
[1] Grimley E, et al. Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain. ACS Chem Biol. 2017;12(3):724-734. DOI:10.1021/acschembio.6b00782 |
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| Company Name: |
DC Chemicals
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| Tel: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
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