| Identification | Back Directory | [Name]
9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID | [CAS]
69413-73-6 | [Synonyms]
PROSTAGLANDIN K1
KJWZYMMLVHIVSU-IYCNHOCDSA-N
9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID | [Molecular Formula]
C20H32O5 | [MDL Number]
MFCD00216081 | [MOL File]
69413-73-6.mol | [Molecular Weight]
352.47 |
| Chemical Properties | Back Directory | [solubility ]
DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12, |
| Hazard Information | Back Directory | [Description]
Prostaglandin K1 (PGK1) is a 9,11-diketo analog of PGE1 or PGD1 . It is a PGE2 receptor subtype EP1 agonist that has 387-fold reduced potency compared to PGE2 .1 | [Definition]
ChEBI: PGK1 is a prostanoid. | [References]
1. Ungrin, M.D., Carrière, M.C., Denis, D., et al. Key structural features of prostaglandin E2 and prostanoid analogs involved in binding and activation of the human EP1 prostanoid receptor Mol. Pharmacol. 59(6),1446-1456(2001). |
|
|