| Identification | Back Directory | [Name]
N-De[2-(Methylsulfonyl)ethyl] Lapatinib | [CAS]
697299-82-4 | [Synonyms]
Lapatinib impurity O
Lapatinib Desmesylethyl Imp
Lapatinib Desmesylethyl Impurity
N-De[2-(Methylsulfonyl)ethyl] Lapatinib
[6-(5-AMinoMethylfuran-2-yl)quinazolin-4-yl][3-chloro-
4-(3-fluorobenzyloxy)phenyl]aMine
6-(5-(aminomethyl)furan-2-yl)-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine
6-[5-(AMinoMethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-4-quinazolinaMine
4-Quinazolinamine, 6-[5-(aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]- | [Molecular Formula]
C26H20ClFN4O2 | [MDL Number]
MFCD30720442 | [MOL File]
697299-82-4.mol | [Molecular Weight]
474.91 |
| Chemical Properties | Back Directory | [Melting point ]
>141oC (dec.) | [Boiling point ]
626.4±55.0 °C(Predicted) | [density ]
1.376±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
8.83±0.29(Predicted) | [color ]
Pale Yellow to Light Beige |
| Hazard Information | Back Directory | [Uses]
A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites. |
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| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
|