ChemicalBook--->CAS DataBase List--->700367-34-6

700367-34-6

700367-34-6 Structure

700367-34-6 Structure
IdentificationBack Directory
[Name]

Docetaxel Hydrate
[CAS]

700367-34-6
[Synonyms]

Paclitaxel Impurity 104
[Molecular Formula]

C43H53NO14
[MOL File]

700367-34-6.mol
[Molecular Weight]

807.879
Chemical PropertiesBack Directory
[Melting point ]

170-174°C
[storage temp. ]

-20°C Freezer
[solubility ]

DMF: 5 mg/ml,DMSO: 5 mg/ml,DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml,Ethanol: 1.5 mg/ml
[form ]

A crystalline solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS08
[Signal word ]

Warning
[Hazard statements ]

H361
[Precautionary statements ]

P201-P202-P280-P308+P313-P405-P501
Hazard InformationBack Directory
[Description]

Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM). It has proven more effective than taxol in preventing the proliferation of cancer cells. Docetaxel has applications in breast cancer and hormone-refractory prostate cancer. This product is intended for research applications.
[Chemical Properties]

White Solid
[Uses]

A semisynthetic derivative of Paclitaxel(P132500), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic.
[Uses]

A semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antineoplastic.
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