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70351-51-8

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70351-51-8 Structure

70351-51-8 Structure
IdentificationBack Directory
[Name]

1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one
[CAS]

70351-51-8
[Synonyms]

Supercinnamaldehyde
1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one
2H-Indol-2-one, 1,3-dihydro-1-methyl-3-(2-oxopropylidene)-
[Molecular Formula]

C12H11NO2
[MDL Number]

MFCD08530327
[MOL File]

70351-51-8.mol
[Molecular Weight]

201.22
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble10mg/mL, clear
[form ]

powder
[color ]

faint red to very dark red
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38-52/53
[Safety Statements ]

26-36/37-61
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Supercinnamaldehyde may be used in transient receptor potential ankyrin 1 (TRPA 1)-mediated cell signaling studies.
[Biochem/physiol Actions]

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC50 = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.
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