| Identification | Back Directory | [Name]
15(S)-HPETE | [CAS]
70981-96-3 | [Synonyms]
15(S)-HPETE
15(S)-HpETE Lipid Maps MS Standard
15-Hydroxyeicosa-5Z,8Z,11Z,13E-tetraenoic acid
15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-*eicosatetraeno
15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-*EICOS ATETRAENOIC
15(S)-HYDROPEROXYEICOSA-5Z,8Z,11Z,13E-TETRAENOIC ACID
15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-EICOSATETRAENOIC ACID
(S-(E,Z,Z,Z))-15-Hydroperoxy-5,8,11,13-eicosatetraenoic acid
5,8,11,13-Eicosatetraenoic acid, 15-hydroperoxy-, (S-(E,Z,Z,Z))-
5,8,11,13-Eicosatetraenoic acid, 15-hydroperoxy-, (5Z,8Z,11Z,13E,15S)-
15(S)-Hydroperoxy-5(Z),8(Z),11(Z),13(E)-eicosatetraenoic acid [15(S)-HPETE]
15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-EICOSATETRAENOIC ACID (2MG/ML ETHANOL SOLUTION) | [EINECS(EC#)]
633-223-2 | [Molecular Formula]
C20H32O4 | [MDL Number]
MFCD00063577 | [MOL File]
70981-96-3.mol | [Molecular Weight]
336.47 |
| Chemical Properties | Back Directory | [Fp ]
14 °C | [storage temp. ]
−70°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml |
| Hazard Information | Back Directory | [Uses]
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 or reduced to 15(S)-HETE by peroxidases. 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1. 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO. | [Uses]
15(S)-HPETE is a primary metabolite of arachidonic acid shown to inhibit arachidonic acid induced platelet aggregation. | [Definition]
ChEBI: The (S)-enantiomer of 15-HPETE. | [storage]
Store at -80°C, protect from light |
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