Identification | Back Directory | [Name]
Gonadorelin acetate | [CAS]
71447-49-9 | [Synonyms]
Ovarelin Cystorelin lhrhdiacetate Gonadorelni Acetate gonadorelindiacetate Gonadorelin 2mg/vial Gonadorelllin Acetate Gonadorelin Acetate RS Gonadorelin acetate, >=98% LH-RH HUMAN DIACETATE SALT Gonadorelin?Acetate impurity Gonadorelin acetate USP/EP/BP GNRH (PORCINE, RAT) 2ACOH 4H2O TIANFU-CHEM - Gonadorelin acetate LH-RH (HUMAN) (PORCINE, RAT) 2ACOH 4H2O Gonadorelin Acetate (33515-09-2 free base) LUTEINIZING HORMONE-RELEASING FACTOR ACETATE Luteinizinghormonereleasinghormonehumanacetatesal Luteinizing hormone-releasing factor, acetate salt luteinizinghormone-releasinghormone,diacetate(salt) LUTEINIZING HORMONE RELEASING HORMONE*AC ETATE GAMMA LUTEINIZING HORMONE RELEASING HORMONE*HU MAN ACETATE PYR-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY-NH2 2ACOH 4H2O Luteinizing Hormone-Releasing Hormone human acetate salt Gonadoliberin, Gonadotropin releasing hormone, LH-RH GONADOTROPIN-RELEASING HORMONE (PORCINE, RAT) 2ACOH 4H2O PGLU-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY-NH2 DIACETATE SALT Luteinizing hormone-releasing factor (swine), acetate (salt) Luteinizing horMone releasing horMone huMan acetate salt(LHRH) LUTEINIZING HORMONE RELEASING HORMONE (HUMAN) (PORCINE, RAT) 2ACOH 4H2O N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[[(2-amino-2-oxoethyl)amino]-oxomethyl]-1-pyrrolidinyl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]ami | [EINECS(EC#)]
636-116-9 | [Molecular Formula]
C57H79N17O15 | [MDL Number]
MFCD00133489 | [MOL File]
71447-49-9.mol | [Molecular Weight]
1242.36 |
Questions And Answer | Back Directory | [Stability]
Gonadorelin acetate is stable for at least 12 months at 24 degrees Celsius and 50 per cent relative humidity and does not degrade even under accelerated storage conditions. Similarly, the lyophilised product has shown excellent stability when stored at 24 °C at 50% relative humidity for at least 18 months. The reconstituted gonadotropin acetate is stable for at least 45 days at 24 °C or 37 °C. The reconstituted gonadotropin acetate is stable for at least 12 months at 24 °C and 50% relative humidity. |
Hazard Information | Back Directory | [Uses]
Luteinizing hormone releasing hormone human acetate salt has been used:
- for synchronization of the ovulations
- for pre-absorption of the anti-GnRH antibody in staining procedures
- to study pituitary sensitivity to GnRH in presence of endocrine disrupting compound
| [Application]
Gonadorelin acetate is widely used in the diagnosis of central precocious puberty. | [Biochem/physiol Actions]
Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions. | [Side effects]
Gonadorelin acetate is usually considered a safe medication. However, severe anaphylactic shock may occur after intravenous administration, manifested by loss of consciousness and tonic convulsions of the arms and legs; prompt treatment with epinephrine, diphenhydramine and fluids restores vital signs within 30 minutes. Therefore, it is recommended that these drugs be administered in an environment that is capable of handling systemic reactions. |
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