ChemicalBook--->CAS DataBase List--->71447-49-9

71447-49-9

71447-49-9 Structure

71447-49-9 Structure
IdentificationBack Directory
[Name]

Gonadorelin acetate
[CAS]

71447-49-9
[Synonyms]

Ovarelin
Cystorelin
lhrhdiacetate
Gonadorelni Acetate
gonadorelindiacetate
Gonadorelin 2mg/vial
Gonadorelllin Acetate
Gonadorelin Acetate RS
Gonadorelin acetate, >=98%
LH-RH HUMAN DIACETATE SALT
Gonadorelin?Acetate impurity
Gonadorelin acetate USP/EP/BP
GNRH (PORCINE, RAT) 2ACOH 4H2O
TIANFU-CHEM - Gonadorelin acetate
LH-RH (HUMAN) (PORCINE, RAT) 2ACOH 4H2O
Gonadorelin Acetate (33515-09-2 free base)
LUTEINIZING HORMONE-RELEASING FACTOR ACETATE
Luteinizinghormonereleasinghormonehumanacetatesal
Luteinizing hormone-releasing factor, acetate salt
luteinizinghormone-releasinghormone,diacetate(salt)
LUTEINIZING HORMONE RELEASING HORMONE*AC ETATE GAMMA
LUTEINIZING HORMONE RELEASING HORMONE*HU MAN ACETATE
PYR-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY-NH2 2ACOH 4H2O
Luteinizing Hormone-Releasing Hormone human acetate salt
Gonadoliberin, Gonadotropin releasing hormone, LH-RH
GONADOTROPIN-RELEASING HORMONE (PORCINE, RAT) 2ACOH 4H2O
PGLU-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY-NH2 DIACETATE SALT
Luteinizing hormone-releasing factor (swine), acetate (salt)
Luteinizing horMone releasing horMone huMan acetate salt(LHRH)
LUTEINIZING HORMONE RELEASING HORMONE (HUMAN) (PORCINE, RAT) 2ACOH 4H2O
N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[[(2-amino-2-oxoethyl)amino]-oxomethyl]-1-pyrrolidinyl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]ami
[EINECS(EC#)]

636-116-9
[Molecular Formula]

C57H79N17O15
[MDL Number]

MFCD00133489
[MOL File]

71447-49-9.mol
[Molecular Weight]

1242.36
Questions And AnswerBack Directory
[Stability]

Gonadorelin acetate is stable for at least 12 months at 24 degrees Celsius and 50 per cent relative humidity and does not degrade even under accelerated storage conditions. Similarly, the lyophilised product has shown excellent stability when stored at 24 °C at 50% relative humidity for at least 18 months. The reconstituted gonadotropin acetate is stable for at least 45 days at 24 °C or 37 °C. The reconstituted gonadotropin acetate is stable for at least 12 months at 24 °C and 50% relative humidity.
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

H2O: 25 mg/mL, clear, faintly yellow
[form ]

powder
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

60
[Safety Statements ]

53-45
[WGK Germany ]

3
[RTECS ]

OK6470000
[F ]

10-21
Hazard InformationBack Directory
[Uses]

Luteinizing hormone releasing hormone human acetate salt has been used:
  • for synchronization of the ovulations
  • for pre-absorption of the anti-GnRH antibody in staining procedures
  • to study pituitary sensitivity to GnRH in presence of endocrine disrupting compound
[Application]

Gonadorelin acetate is widely used in the diagnosis of central precocious puberty.
[Biochem/physiol Actions]

Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.
[Side effects]

Gonadorelin acetate is usually considered a safe medication. However, severe anaphylactic shock may occur after intravenous administration, manifested by loss of consciousness and tonic convulsions of the arms and legs; prompt treatment with epinephrine, diphenhydramine and fluids restores vital signs within 30 minutes. Therefore, it is recommended that these drugs be administered in an environment that is capable of handling systemic reactions.
Spectrum DetailBack Directory
[Spectrum Detail]

Gonadorelin acetate(71447-49-9)MS
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