Identification | Back Directory | [Name]
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE | [CAS]
71800-36-7 | [Synonyms]
1-9-Kallidin des-arg(10)-kallidi (DES-ARG10)-KALLIDIN Lys-[Des-Arg9]Bradyk kallidin, des-Arg(10)- LYS-(DES-ARG9)-BRADYKININ LYSYL-DES-ARG9-BRADYKININ [DES-ARG9,LYS0]-BRADYKININ [LYS0, DES-ARG9]-BRADYKININ LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE H-Lys-Arg-Pro-Pro-Gly-Per-Pro-Phe-OH H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-OH LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE USP/EP/BP LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE: KRPPGFSPF Lys-(Des-Arg9)-Bradykinin
(Des-Arg10)-Kallidin | [Molecular Formula]
C50H73N13O11 | [MDL Number]
MFCD00079826 | [MOL File]
71800-36-7.mol | [Molecular Weight]
1032.2 |
Hazard Information | Back Directory | [Uses]
[Lys-des-Arg9]-Bradykinin has been used as a B1R agonist to investigate the role of B1R in diabetes-induced secondary hemorrhage. | [Biochem/physiol Actions]
[Des-Arg10]-kallidin or [Lys-des-Arg9]-Bradykinin is a bradykinin B1 receptor agonist. It strongly upregulates the B1 receptor and is blocked by a specific protein kinase C inhibitor. The upregulation is correlated with the induction of transcription nuclear factor κB (NF-κB). Elevation of Lys-des[Arg9]–bradykinin because of airway inflammation in asthma patients is known to modify the immune responses. It affects the migration and production of interleukin-12 in monocyte-derived dendritic cells. | [storage]
Store at -20°C |
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