ChemicalBook--->CAS DataBase List--->71800-36-7

71800-36-7

71800-36-7 Structure

71800-36-7 Structure
IdentificationBack Directory
[Name]

LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
[CAS]

71800-36-7
[Synonyms]

1-9-Kallidin
des-arg(10)-kallidi
(DES-ARG10)-KALLIDIN
Lys-[Des-Arg9]Bradyk
kallidin, des-Arg(10)-
LYS-(DES-ARG9)-BRADYKININ
LYSYL-DES-ARG9-BRADYKININ
[DES-ARG9,LYS0]-BRADYKININ
[LYS0, DES-ARG9]-BRADYKININ
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
H-Lys-Arg-Pro-Pro-Gly-Per-Pro-Phe-OH
H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-OH
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE USP/EP/BP
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE: KRPPGFSPF
Lys-(Des-Arg9)-Bradykinin (Des-Arg10)-Kallidin
[Molecular Formula]

C50H73N13O11
[MDL Number]

MFCD00079826
[MOL File]

71800-36-7.mol
[Molecular Weight]

1032.2
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

Powder
[Water Solubility ]

Soluble to 1 mg/ml in water
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

[Lys-des-Arg9]-Bradykinin has been used as a B1R agonist to investigate the role of B1R in diabetes-induced secondary hemorrhage.
[Biochem/physiol Actions]

[Des-Arg10]-kallidin or [Lys-des-Arg9]-Bradykinin is a bradykinin B1 receptor agonist. It strongly upregulates the B1 receptor and is blocked by a specific protein kinase C inhibitor. The upregulation is correlated with the induction of transcription nuclear factor κB (NF-κB). Elevation of Lys-des[Arg9]–bradykinin because of airway inflammation in asthma patients is known to modify the immune responses. It affects the migration and production of interleukin-12 in monocyte-derived dendritic cells.
[storage]

Store at -20°C
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