| Identification | Back Directory | [Name]
1-Methoxy-9H-carbazole-3-carbaldehyde | [CAS]
723-97-7 | [Synonyms]
Murrayanine
1-Methoxy-9H-carbazole-3-carbaldehyde
9H-Carbazole-3-carboxaldehyde, 1-methoxy- | [Molecular Formula]
C14H11NO2 | [MDL Number]
MFCD18452404 | [MOL File]
723-97-7.mol | [Molecular Weight]
225.24 |
| Hazard Information | Back Directory | [Description]
This simple carbazole alkaloid is found in the stem bark of Mu"aya koenigii
Spreng. It is best purified by sublimation of the crude base when it yields colour_x0002_less crystals. The ultraviolet spectrum in ethanol has absorption maxima at 238,
247,274,289 and 335 mJJ.. The structure has been shown to be 3-formyl-lmethoxycarbazole by spectroscopic methods and synthesis. It yields an oxime,
m.p. l55-6°C; a picrate, m.p. 198-2000 C and the 2:4-dinitrophenylhydrazone,
m.p. > 300°C. The N-methyl derivative forms colourless needles from C6H6-
light petroleum, m.p. l48-9°C. When subjected to Wolff-Kishner reduction, the
alkaline phase yields l-hydroxy-3-methyl-carbazole. | [Uses]
Murrayanine is a carbazole alkaloid. Murrayanine suppresses the proliferation and metastasis of human breast cancer cells via induction of apoptosis and inhibition of RANK/RANKL signaling pathway. | [Definition]
ChEBI: A natural product found in Clausena harmandiana. | [References]
Chakraborty, Barman, Bose., Tetrahedron, 21, 681 (1965)
Synthesis:
Crum, Sprague., Chern. Cornrnun., 417 (1966)
Chakraborty, Chowdhury., J. Org. Chern., 33, 1265 (1968) |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
|