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72822-13-0

72822-13-0 Structure

72822-13-0 Structure
IdentificationBack Directory
[Name]

Dapiprazole Hydrochloride
[CAS]

72822-13-0
[Synonyms]

AF 2139
Reversil
Rev-eyes
GlaMidolo
Reversil Hydrochloride
Glamidolo Hydrochloride
DAPIPRAZOLE HYDROCHLORIDE
Dapiprazole monohydrochloride
3-(2-(4-(o-tolyl)piperazin-1-yl)ethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine hydrochloride
5,6,7,8-Tetrahydro-3-[2-[4-(2-Methylphenyl)-1-piperazinyl]ethyl]-1,2,4-Triazolo[4,3-a]pyridine Hydrochloride
3-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine,hydrochloride
1,2,4-Triazolo(4,3-A)pyridine, 5,6,7,8-tetrahydro-3-(2-(4-(2-methylphenyl)-1-piperazinyl)ethyl)-, monohydrochloride
[Molecular Formula]

C19H28ClN5
[MDL Number]

MFCD00941400
[MOL File]

72822-13-0.mol
[Molecular Weight]

361.912
Chemical PropertiesBack Directory
[Description]

Dapiprazole is a new anti-glaucoma agent especially useful in the treatment of narrow-angle glaucoma. It is also reported to have antipsychotic activity potentially devoid of extrapyramidal symptoms.
[Melting point ]

206-207°
[storage temp. ]

2-8°C
[solubility ]

Chloroform, Methanol
[form ]

powder
[color ]

white to beige
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Originator]

Angelini (Italy)
[Uses]

Dapiprazole is an alpha blocker. Dapiprazole is used in the reversal of diagnostic mydriasis.
[Brand name]

Glamidolo
[Brand name]

Rev-Eyes (Angelini).
[Biochem/physiol Actions]

Dapiprazole hydrochloride is an an α-adrenergic blocking agent that is used to reverse mydriasis after eye examination.
Safety DataBack Directory
[Toxicity]

LD50 in mice (mg/kg): 260 i.p. (Silvestrini)
Spectrum DetailBack Directory
[Spectrum Detail]

Dapiprazole Hydrochloride(72822-13-0)1HNMR
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