| Identification | Back Directory | [Name]
N-nitrosothiazolidine | [CAS]
73870-33-4 | [Synonyms]
NITROSOTHIAZOLIDINE
3-NITROSOTHIAZOLIDINE
N-nitrosothiazolidine
Thiazolidine, 3-nitroso-
N-NITROSO-1,3-THIAZOLIDINE | [Molecular Formula]
C3H6N2OS | [MOL File]
73870-33-4.mol | [Molecular Weight]
118.16 |
| Hazard Information | Back Directory | [Uses]
3-Nitrosothiazolidine is a nitrosamine present in food products, a carcinogenic substance. | [Definition]
ChEBI: N-nitroso-1,3-thiazolidine is a nitrosamine and a member of thiazolidines. | [Safety Profile]
Moderately toxic by ingestion. Mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits very toxic fumes of NOx and SOx. | [Metabolic pathway]
N-Nitroso-1,3-thiazolidine administered by gavage to
rats is excreted mostly in the urine with a small
amount in respired air. The major metabolite in the
urine is 2-hydroxy-1,3-thiazolidine, and minor
quantities of the isomers 4- and 5-hydroxy-1,3-
thiazolidines are detected. The presence of
hydroxy-1,3-thiazolidine indicates that a-hydroxylation
and denitrosation are major metabolic pathways of
N-nitroso-1,3-thiazolidine. |
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