| Identification | Back Directory | [Name]
GSK-3 Inhibitor X | [CAS]
740841-15-0 | [Synonyms]
(E/Z)-BIO-acetoxime
GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem
2H-Indol-2-one, 3-[3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro- | [Molecular Formula]
C18H12BrN3O3 | [MOL File]
740841-15-0.mol | [Molecular Weight]
398.21 |
| Hazard Information | Back Directory | [General Description]
An acetoxime analog of BIO, GSK-3 Inhibitor IX (Cat. No. 361550) that exhibits greater selectivity for GSK-3α/β (IC50 = 10 nM) over Cdk5/p25, Cdk2/cyclin A, and Cdk1/cyclin B (IC50 = 2.4 μM, 4.3 μM, and 63 μM, respectively). A weak inhibitor of Cdk4/cyclin D1 and many other non-related kinases (IC50 ≥ 10 μM). Yields BIO (Cat. No. 361550) upon hydrolysis. | [Biochem/physiol Actions]
Product does not compete with ATP. |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
D&C Chemicals
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+86-21-58447131 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList16963/0.htm |
| Company Name: |
Creative Enzymes
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| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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