| Identification | Back Directory | [Name]
11-deoxy-15-keto-13,14-dihydro-11 beta,16-cycloprostaglandin E2 | [CAS]
74158-09-1 | [Synonyms]
11-deoxy-15-keto-13,14-dihydro-11 beta,16-cycloprostaglandin E2
(E)-7-(4-butyl-2,5-dioxooctahydro-1H-inden-1-yl)hept-5-enoic acid | [Molecular Formula]
C20H30O4 | [MOL File]
74158-09-1.mol | [Molecular Weight]
334.45 |
| Hazard Information | Back Directory | [Uses]
Bicyclo prostaglandin E2 (bicyclo PGE2) is a stable breakdown product of PGE2 and 13,14-dihydro-15-keto PGE2 . Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2 found in human plasma at a median level of 20-25 pg/ml. Due to the inherent instability of 13,14-dihydro-15-keto PGE2, it is advisable to quantify it as bicyclo PGE2 to estimate PGE2 biosynthesis or metabolism in vivo. |
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