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75187-63-2

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75187-63-2 Structure

75187-63-2 Structure
IdentificationBack Directory
[Name]

7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE
[CAS]

75187-63-2
[Synonyms]

YN1
YN1 >=98% (HPLC)
4',7,8-Trihydroxy isoflavone
7,8-Dihydroxy-3-(4-hydroxy-pheny
7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE
7,8-dihydroxy-3-(4-hydroxyphenyl)-4h-chroMen-4-one
7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE 98%
4H-1-Benzopyran-4-one,7,8-dihydroxy-3-(4-hydroxyphenyl)-
[Molecular Formula]

C15H10O5
[MDL Number]

MFCD00885567
[MOL File]

75187-63-2.mol
[Molecular Weight]

270.24
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble10mg/mL, clear
[form ]

powder
[color ]

white to beige
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

25
[Safety Statements ]

45
[RIDADR ]

UN 2811 6.1 / PGIII
[WGK Germany ]

3
[HS Code ]

2932990090
Hazard InformationBack Directory
[Definition]

ChEBI: 8-Hydroxydaidzein is a member of isoflavones.
[Biochem/physiol Actions]

YN1 is a potent inhibitor of PFKFB3 (6-Phosphfructo-2-kinase/fructose-2,6-bisphosphatase: IC50 = 670 nM). PFKFB3 is over expressed in many cancers, and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YN1 inhibits glycolysis and proliferation in HeLa cells.
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