Identification | Back Directory | [Name]
(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE | [CAS]
75614-87-8 | [Synonyms]
(R)-(-)-a-Methylhist (R)-ALPHA-METHYLHISTAMIN 2HBR R(-)-ALPHA-METHYLHISTAMINE 2HBR -Methylhistamine dihydrobromide ( R ) -alpha-Methylhistamin x 2HBr R(-)-α-Methylhistamine Dihydrobromide (R)-1-(1H-iMidazol-4-yl)propan-2-aMine HISTAMINE, (R)-(-)-ALPHA-METHYL-, 2HCL (R)-(-)-a-Methylhistaminedihydrobromide (r)(-)-α-methylhistamine dihydrochloride (R)-(-)-A-methylhistamine*dihydrochloride R(-)-ALPHA-METHYLHISTAMINE DIHYDROCHLORIDE [R,(-)]-α-Methyl-1H-imidazole-4-ethanamine 1H-Imidazole-5-ethanamine, α-methyl-, (αR)- (R)-(-)-alpha-Methylhisamine dihydrochloride (R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE Methylhistamine dihydrobromide (R)-(-)-alpha- R-(-)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine HISTAMINE, R(-)-ALPHA-METHYL-, DIHYDROCHLORIDE (alphaR)-alpha-Methyl-1H-imidazole-4-ethanamine r(-)-α-methyl-1h-imidazole-4-ethanamine dihydrochloride (R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide (R)-(-)-a-Methyl-(1H)-imidazole-4-ethanaminedihydrobromide R(-)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE (R)-(-)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROBROMIDE R(-)-α-Methylhistamine
DISCONTINUED. UNSTABLE, OFFER M311990 | [Molecular Formula]
C6H11N3 | [MDL Number]
MFCD00209886 | [MOL File]
75614-87-8.mol | [Molecular Weight]
125.17 |
Hazard Information | Back Directory | [Chemical Properties]
White to off-white solid | [Uses]
R(-)-alpha-Methylhistamine is a potent agonist of the histamine H3-receptor. | [Definition]
ChEBI: An aralkylamino compound that is histamine bearing a methyl substituent at the alpha-position (the R-enantiomer). | [Biological Activity]
Very potent, high affinity H 3?agonist (K D = 50.3 nM) that displays > 200-fold selectivity over H 4 receptors. Inhibits H 3 -mediated histamine synthesis and release in the CNS and stimulates H 4 -mediated eosinophil shape change (EC 50 = 66 nM). Also available as part of the Histamine H 3 Receptor Tocriset™ . |
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