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75614-87-8

75614-87-8 Structure

75614-87-8 Structure
IdentificationBack Directory
[Name]

(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
[CAS]

75614-87-8
[Synonyms]

(R)-(-)-a-Methylhist
(R)-ALPHA-METHYLHISTAMIN 2HBR
R(-)-ALPHA-METHYLHISTAMINE 2HBR
-Methylhistamine dihydrobromide
( R ) -alpha-Methylhistamin x 2HBr
R(-)-α-Methylhistamine Dihydrobromide
(R)-1-(1H-iMidazol-4-yl)propan-2-aMine
HISTAMINE, (R)-(-)-ALPHA-METHYL-, 2HCL
(R)-(-)-a-Methylhistaminedihydrobromide
(r)(-)-α-methylhistamine dihydrochloride
(R)-(-)-A-methylhistamine*dihydrochloride
R(-)-ALPHA-METHYLHISTAMINE DIHYDROCHLORIDE
[R,(-)]-α-Methyl-1H-imidazole-4-ethanamine
1H-Imidazole-5-ethanamine, α-methyl-, (αR)-
(R)-(-)-alpha-Methylhisamine dihydrochloride
(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE
Methylhistamine dihydrobromide (R)-(-)-alpha-
R-(-)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine
HISTAMINE, R(-)-ALPHA-METHYL-, DIHYDROCHLORIDE
(alphaR)-alpha-Methyl-1H-imidazole-4-ethanamine
r(-)-α-methyl-1h-imidazole-4-ethanamine dihydrochloride
(R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide
(R)-(-)-a-Methyl-(1H)-imidazole-4-ethanaminedihydrobromide
R(-)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROCHLORIDE
(R)-(-)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROBROMIDE
R(-)-α-Methylhistamine DISCONTINUED. UNSTABLE, OFFER M311990
[Molecular Formula]

C6H11N3
[MDL Number]

MFCD00209886
[MOL File]

75614-87-8.mol
[Molecular Weight]

125.17
Chemical PropertiesBack Directory
[density ]

1.094
[storage temp. ]

Desiccate at RT
[solubility ]

H2O: soluble
[form ]

solid
[color ]

white to off-white
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
[HS Code ]

29332900
Hazard InformationBack Directory
[Chemical Properties]

White to off-white solid
[Uses]

R(-)-alpha-Methylhistamine is a potent agonist of the histamine H3-receptor.
[Definition]

ChEBI: An aralkylamino compound that is histamine bearing a methyl substituent at the alpha-position (the R-enantiomer).
[Biological Activity]

Very potent, high affinity H 3?agonist (K D = 50.3 nM) that displays > 200-fold selectivity over H 4 receptors. Inhibits H 3 -mediated histamine synthesis and release in the CNS and stimulates H 4 -mediated eosinophil shape change (EC 50 = 66 nM). Also available as part of the Histamine H 3 Receptor Tocriset™ .
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