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ChemicalBook--->CAS DataBase List--->760930-59-4

760930-59-4

760930-59-4 Structure

760930-59-4 Structure
IdentificationBack Directory
[Name]

Crotonyl fentanyl
[CAS]

760930-59-4
[Synonyms]

Crotonyl fentanyl
Crotonyl fentanyl (CRM)
2-Butenamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-, (2E)-
[Molecular Formula]

C23H28N2O
[MOL File]

760930-59-4.mol
[Molecular Weight]

348.48
Chemical PropertiesBack Directory
[solubility ]

DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ]

A neat solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H312-H302-H332
[Precautionary statements ]

P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501
[DEA Controlled Substances]

CSCN: 9844
CSA SCH: Schedule I
NARC: Yes
Hazard InformationBack Directory
[Description]

Crotonyl fentanyl is an analytical reference material categorized as an opioid.1,2,3 Crotonyl fentanyl induces generalized responses in mice trained to discriminate oxycodone from saline.4 Crotonyl fentanyl is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.
[Uses]

Crotonyl Fentanyl is an analog of Fentanyl (F274990), which is a controlled substanced used as analgesic.
[References]

1. Eshleman, A.J., Nagarajan, S., Wolfrum, K.M., et al. Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors Biochem. Pharmacol. 182,114293(2020).
2. Vasudevan, L., Vandeputte, M.M., Deventer, M., et al. Assessment of structure-activity relationships and biased agonism at the mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform Biochem. Pharmacol. 177,113910(2020).
3. Varshneya, N.B., Walentiny, D.M., Moisa, L.T., et al. Opioid-like antinociceptive and locomotor effects of emerging fentanyl-related substances Neuropharmacology 151,171-179(2019).
4. Walentiny, D.M., Moisa, L.T., and Beardsley, P.M. Oxycodone-like discriminative stimulus effects of fentanyl-related emerging drugs of abuse in mice Neuropharmacology 150,210-216(2019).
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