| Identification | Back Directory | [Name]
nodusmicin | [CAS]
76265-48-0 | [Synonyms]
U 59761
nodusmicin
11,14b-Epoxy-14bH-naphth[2,1-e]oxecin-6(7H)-one, 3,4,8,8a,10a,11,12,13,14,14a-decahydro-12,14-dihydroxy-4-[(1R)-1-hydroxyethyl]-7-methoxy-1,3,13-trimethyl-, (1E,3R,4S,7S,8aS,10aR,11R,12R,13R,14R,14aS,14bS)- (9CI) | [Molecular Formula]
C23H34O7 | [MDL Number]
MFCD28898540 | [MOL File]
76265-48-0.mol | [Molecular Weight]
422.51 |
| Hazard Information | Back Directory | [Description]
Nodusmicin is a macrolide antibiotic. It has activity against antibiotic-susceptible and -resistant S. aureus with MIC values of 125, 250, and 250 μg/ml for UC-76, UC-6685, and UC-6690 strains, respectively. | [Uses]
Nodusmicin is a co-metabolite of nargenicin, bearing the core macrocyclic lactone but lacking the pyrrole ester. Like nargenicin, nodusmicin is a potent antibiotic active against both aerobic and anaerobic bacteria. Lack of availability has restricted a more extensive investigation of nodusmicin. | [Uses]
Nodusmicin is a potent antibiotic against aerobic and anaerobic bacteria. |
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