| Identification | Back Directory | [Name]
BETA-NEOENDORPHIN | [CAS]
77739-21-0 | [Synonyms]
B-neoendorphin
β-Neo-Endorphin
BETA-NEOENDORPHIN
β-Neoendorphin (human)
β-Neo-Endorphin (Porcine)
BETA-NEO-ENDORPHIN (PORCINE)
TYR-GLY-GLY-PHE-LEU-ARG-LYS-TYR-PRO
PRODYNORPHIN (175-183) (HUMAN, PORCINE)
H-TYR-GLY-GLY-PHE-LEU-ARG-LYS-TYR-PRO-OH
TYR-GLY-GLY-PHE-LEU-ARG-LYS-TYR-PRO: YGGFLRKYP
L-Tyr-Gly-Gly-L-Phe-L-Leu-L-Arg-L-Lys-L-Tyr-L-Pro-OH
β-Neoendorphin, Prodynorphin (175-183) (human, porcine)
β-Neoendorphin, Prodynorphin (175-183) (human, porcine)
L-Proline, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-lysyl-L-tyrosyl-
((S)-2-((S)-2-((S)-2-(2-(2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)acetamido)acetamido)-3-phenylpropanamido)-4-methylpentanamido)-5-((diaminomethylene)amino)pentanoyl)-L-lysyl-L-tyrosyl-L-proline | [Molecular Formula]
C54H77N13O12 | [MDL Number]
MFCD00076401 | [MOL File]
77739-21-0.mol | [Molecular Weight]
1100.27 |
| Hazard Information | Back Directory | [Definition]
Pro-dynorphin (also referred to as pro-enkephalin B) can be processed to produce dynorphin A, dynorphin B, α-neoendorphin, and β-neoendorphin. Beta-Neoendorphin is an endogenous opioid peptide. Beta-Neoendorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. It shows activation of the Erk1/2, MMP-2 and MMP-9. The carboxypeptidase cleavage step is not rate limiting for the production of most neuroendocrine peptides, the exceptions being the conversion of α-neoendorphin into β-neoendorphin, which requires cleavage of a Pro-Lys bond, and the generation of rat β-endorphin 1-26, which requires cleavage of a C-terminal His-27 residue.
|
|
|