| Identification | Back Directory | [Name]
N1-ACETYLSPERMINE TRIHYDROCHLORIDE | [CAS]
77928-70-2 | [Synonyms]
1-ACETYLSPERMINE TRIHYDROCHLORIDE
N1-Acetylspermine (hydrochloride)
N1-ACETYLSPERMINE TRIHYDROCHLORIDE
N-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)acetamide trihydrochloride | [Molecular Formula]
C12H31Cl3N4O | [MDL Number]
MFCD00083219 | [MOL File]
77928-70-2.mol | [Molecular Weight]
353.76 |
| Chemical Properties | Back Directory | [Melting point ]
>256°C (dec.) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [BRN ]
7052482 |
| Hazard Information | Back Directory | [Description]
N1-Acetylspermine is a monoacetylated derivative of spermine , an endogenous polyamine synthesized from spermidine , that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. N1-Acetylspermine has been used to study the uptake of the anticancer polyamine analog bleomycin-A5 by the human carnitine transporter SLC22A16. | [Uses]
N1-Acetylspermine trihydrochloride has been used in a study to determine that the human carnitine transporter SLC22A16 mediates high affinity uptake of the anticancer polyamine analogue bleomycin-A5. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
amyjetsci
|
| Tel: |
027-59626688 18771149750 |
| Website: |
https://www.amyjet.com/ |
|