| Identification | Back Directory | [Name]
Methanone, (2-butyl-3-benzofuranyl)[3,5-diiodo-4-[3-(1-pyrrolidinyl)propoxy]phenyl]- | [CAS]
782387-91-1 | [Synonyms]
ADTL-SA1215
Methanone, (2-butyl-3-benzofuranyl)[3,5-diiodo-4-[3-(1-pyrrolidinyl)propoxy]phenyl]- | [Molecular Formula]
C26H29I2NO3 | [MOL File]
782387-91-1.mol | [Molecular Weight]
657.32 |
| Chemical Properties | Back Directory | [Boiling point ]
661.3±55.0 °C(Predicted) | [density ]
1.614±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
10.10±0.20(Predicted) | [color ]
Light brown to brown |
| Hazard Information | Back Directory | [Biological Activity]
ADTL-SA1215 is a first-in-class specific small-molecule activator of SIRT3 that modulates autophagy in triple negative breast cancer. | [References]
[1]. Zhang J, et al. Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer. J Med Chem. 2021 Oct 14;64(19):14192-14216. |
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