| Identification | Back Directory | [Name]
N-(4,6,7-TRIMETHYLQUINAZOLIN-2-YL)GUANIDINE | [CAS]
784-90-7 | [Synonyms]
STK033079
TOS-BB-1276
BAS 00501778
MLS000688740
SMR000284641
ASISCHEM N46336
AKOS BBS-00005668
A2B receptor antagonist 2
N-(4,6,7-TRIMETHYLQUINAZOLIN-2-YL)GUANIDINE
1-(4,6,7-Trimethylquinazolin-2-yl)guanidine
2-(4,6,7-trimethyl-2-quinazolinyl)guanidine
2-(4,6,7-trimethylquinazolin-2-yl)guanidine
Guanidine, (4,6,7-trimethyl-2-quinazolinyl)- | [Molecular Formula]
C12H15N5 | [MDL Number]
MFCD00981386 | [MOL File]
784-90-7.mol | [Molecular Weight]
229.28 |
| Chemical Properties | Back Directory | [Melting point ]
259-260 °C (decomp) | [Boiling point ]
435.9±55.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
Methanol : 5 mg/mL (21.81 mM; ultrasonic and warming and heat to 60°C)|DMSO : 2 mg/mL (8.72 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [pka]
8.13±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Definition]
ChEBI: 2-(4,6,7-Trimethyl-2-quinazolinyl)guanidine is a member of quinazolines. | [Biological Activity]
A2B receptor antagonist 2 (compound 18) is an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively[1]. | [storage]
4°C, protect from light | [References]
[1]. Thomas R Webb, et al. Quinazolines as adenosine receptor antagonists: SAR and selectivity for A2B receptors. Bioorg Med Chem. 2003 Jan 2;11(1):77-85. |
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