| Identification | Back Directory | [Name]
NORBUPRENORPHINE | [CAS]
78715-23-8 | [Synonyms]
NORBUPRENORPHINE
N-Dealkylbuprenorphine
N-Desalkylbuprenorphin
Norbuprenorphine (CRM)
N-Desalkylbuprenorphine
Buprenorphine Impurity B
Norbuprenorphine solution
N-De(cyclopropylmethyl)buprenorphine
N-Des(cyclopropylmethyl)buprenorphine
Buprenorphine Hydrochloride Impurity B
Norbuprenorphine (1.0 Mg/ML in Methanol)
Buprenorphine Hydrochloride EP Impurity B
(αS)-α-tert-Butyl-4,5α-epoxy-3-hydroxy-6-methoxy-α-methyl-6β,14-ethanomorphinan-7α-methanol
(2S)-2-(4,5α-epoxy-3-hydroxy-6-methoxy-6α,14-ethano-14α-morphinan-7α-yl)-3,3-dimethylbutan-2-ol (norbuprenorphine),
(αS,5α,7α)-α-(1,1-DiMethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-Methoxy-α-Methyl-6,14-ethenoMorphinan-7-Methanol
(aS,5a,7a)-a-(1,1-Dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-a-methyl-6,14-ethenomorphinan-7-methanol
6,14-Ethenomorphinan-7-methanol, α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, (αS,5α,7α)-
6,14-Ethenomorphinan-7-methanol, .alpha.-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-.alpha.-methyl-, (.alpha.S,5.alpha.,7.alpha.)- | [EINECS(EC#)]
200-659-6 | [Molecular Formula]
C25H35NO4 | [MDL Number]
MFCD00190626 | [MOL File]
78715-23-8.mol | [Molecular Weight]
413.55 |
| Chemical Properties | Back Directory | [Melting point ]
221-224°C | [Boiling point ]
562.7±50.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [Fp ]
9℃ | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
A neat solid | [pka]
9.14±0.60(Predicted) |
| Hazard Information | Back Directory | [Description]
Norbuprenorphine (CRM) (Item No. 20127) is a certified reference material categorized as an opioid. It is a major active metabolite of buprenorphine (Item Nos. 14025 | ISO60178). This product is intended for research and forensic applications. | [Chemical Properties]
Light Brown Solid | [Uses]
A metabolite of Buprenorphine | [Definition]
ChEBI: Norbuprenorphine is a member of phenanthrenes. | [References]
[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[2] E J CONE. The metabolism and excretion of buprenorphine in humans.[J]. Drug Metabolism and Disposition, 1984, 12 5: 577-581.
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