ChemicalBook--->CAS DataBase List--->79404-91-4

79404-91-4

79404-91-4 Structure

79404-91-4 Structure
IdentificationBack Directory
[Name]

Cilofungin
[CAS]

79404-91-4
[Synonyms]

LY-121019
Cilofungin
Antibiotic LY-121019
(4R,5R)-N2-[4-(Octyloxy)benzoyl]-4,5-dihydroxycyclo[L-Orn*-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]]
Cyclo[L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]]
Cyclo[L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-]
[Molecular Formula]

C49H71N7O17
[MOL File]

79404-91-4.mol
[Molecular Weight]

1030.13
Chemical PropertiesBack Directory
[Melting point ]

>165°C (dec.)
[density ]

1.46
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

Antifunga.
[Uses]

Cilofungin is a lipopeptide from echinocandin class of antifungal drugs which inhibits the synthesis of glucan in the fungal cell walls.
[Definition]

ChEBI: A cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus spp. By inhibiting the conversion of lanosterol to ergosterol, it invades a fungus' ability to synthesize cell walls. A modified form of echinocandin B, it is an antimycoti agent against Candida albicans.
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