Identification | Back Directory | [Name]
Cilofungin | [CAS]
79404-91-4 | [Synonyms]
LY-121019 Cilofungin Antibiotic LY-121019 (4R,5R)-N2-[4-(Octyloxy)benzoyl]-4,5-dihydroxycyclo[L-Orn*-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]] Cyclo[L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]] Cyclo[L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-] | [Molecular Formula]
C49H71N7O17 | [MOL File]
79404-91-4.mol | [Molecular Weight]
1030.13 |
Chemical Properties | Back Directory | [Melting point ]
>165°C (dec.) | [density ]
1.46 | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic |
Hazard Information | Back Directory | [Uses]
Antifunga. | [Uses]
Cilofungin is a lipopeptide from echinocandin class of antifungal drugs which inhibits the synthesis of glucan in the fungal cell walls. | [Definition]
ChEBI: A cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus spp. By inhibiting the conversion of lanosterol to ergosterol, it invades a fungus' ability to synthesize cell walls. A modified form of echinocandin B, it is an antimycoti
agent against Candida albicans. |
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CHEMICAL LAND21
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