| Identification | Back Directory | [Name]
6-Azido-hexanoic acid | [CAS]
79598-53-1 | [Synonyms]
e-Azidocaproic acid
6-Azido-hexanoic acid
6-Azidohexanoic acid >=95%
6-Azidohexanoic acid - A1945 | [Molecular Formula]
C6H11N3O2 | [MDL Number]
MFCD12406156 | [MOL File]
79598-53-1.mol | [Molecular Weight]
157 |
| Chemical Properties | Back Directory | [density ]
1.074 g/mL | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Oil | [color ]
Colourless to Pale Yellow | [Stability:]
Light Sensitive |
| Hazard Information | Back Directory | [Description]
6-Azido-hexanoic acid is a linker containing an azide group and a terminal carboxylic acid. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Chemical Properties]
Colorless to yellow oil | [Uses]
6-Azidohexanoic acid is a six-carbon saturated fatty acid with an ω-terminal azide group. This building block can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC), forming a stable amide bond. The terminal azide group allows conjugation with compounds containing alkyne groups through a copper(I)-catalyzed cycloaddition reaction, also known as click chemistry. 6-Azidohexanoic acid is useful for crosslinking, synthesis of chemical probes, and other bioconjugation strategies. |
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