ChemicalBook--->CAS DataBase List--->80115-95-3

80115-95-3

80115-95-3 Structure

80115-95-3 Structure
IdentificationBack Directory
[Name]

N-ACETYL LEUKOTRIENE E4
[CAS]

80115-95-3
[Synonyms]

N-AC-LTE4
N-AcetylLTE4
N-ACETYL LEUKOTRIENE E4
leukotriene E4, N-acetyl-
5S-HYDROXY-6R-(S-(N-ACETYL)CYSTEINYL)-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID
(5S,6R,7E,9E,11Z,14Z)-5-Hydroxy-6-[[(R)-2-acetylamino-2-carboxyethyl]thio]-7,9,11,14-icosatetraenoic acid
7,9,11,14-Eicosatetraenoic acid, 6-[[(2R)-2-(acetylamino)-2-carboxyethyl]thio]-5-hydroxy-, (5S,6R,7E,9E,11Z,14Z)-
[Molecular Formula]

C25H39NO6S
[MDL Number]

MFCD00135261
[MOL File]

80115-95-3.mol
[Molecular Weight]

481.65
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 0.1 mg/ml
[form ]

Liquid.
Safety DataBack Directory
[Hazard Codes ]

F,T
[Risk Statements ]

11
[Safety Statements ]

7-16-23-45
[RIDADR ]

UN 1230 3/PG 2
Hazard InformationBack Directory
[Uses]

N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile. This route of metabolism is prominent in the rat, but of minor importance in humans. N-acetyl LTE4 is 100 times less potent than LTC4 as a vasoconstricting agent. In healthy human subjects urinary excretion of N-acetyl LTE4 is about 1.5 nmol/mol creatinine, which is considerably less than that of LTE4 (12 nmol/mol creatinine).
[storage]

Store at -20°C
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