| Identification | Back Directory | [Name]
NSC 50460 | [CAS]
801985-13-7 | [Synonyms]
NSC 50460
BPH-1358 free base
NSC50460 free base
BPH1358 free base,BPH 1358 free base
Staphyloccocus UPPS Inhibitor methanesulfonate
[1,1'-Biphenyl]-4,4'-dicarboxamide, N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-
N4,N4′-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-[1,1′-Biphenyl]-4,4′-dicarboxamide methanesulfonate salt | [Molecular Formula]
C32H28N6O2 | [MDL Number]
MFCD32263018 | [MOL File]
801985-13-7.mol | [Molecular Weight]
528.6 |
| Chemical Properties | Back Directory | [density ]
1.326±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
2-8°C | [solubility ]
H2O: soluble5mg/mL, clear (warmed) | [form ]
powder | [pka]
12.710±0.70(predicted) | [color ]
white to beige | [Water Solubility ]
H2O: 5mg/mL, clear (warmed) |
| Hazard Information | Back Directory | [Biological Activity]
Staphyloccocus UPPS Inhibitor methanesulfonate is a potent inhibitor of the bacteria enzyme undecaprenyl diphosphate synthase (UPPS). Staphyloccocus UPPS Inhibitor kills both wild type and methicillin-resitant strains of Staphylococcus aureus (MRSA). Staphyloccocus UPPS Inhibitor protects mice from death after infection with MRSA. |
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