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81691-06-7

81691-06-7 Structure

81691-06-7 Structure
IdentificationBack Directory
[Name]

3-methylpseudouridine
[CAS]

81691-06-7
[Synonyms]

NSC 363818
3-Methylpsedouridine
3-methylpseudouridine
N3-Methylpseudouridine
3-Methyl-5-beta-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
[Molecular Formula]

C10H14N2O6
[MDL Number]

MFCD26523151
[MOL File]

81691-06-7.mol
[Molecular Weight]

258.228
Questions And AnswerBack Directory
[Uses]

3-Methylpseudouridine is used for increasing viability or longevity of organ or organ explant using modified mRNAs for proteins essential for organ survival.
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Definition]

ChEBI: 3-Methylpseudouridine is a carbohydrate derivative and a nucleobase-containing molecular entity.
[Synthesis]

 ψ-Uridine was trimethylsilylated and the crude product was treated with acetyl chloride, to give the 1-acetyl derivative (3). Crude 3 was methylated with dimethoxymethyldimethylamine and then saponified, to give crystalline 3-methyl-ψ-uridine in 82% overall yield. 
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