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5-cis Iloprost is the C-5 cis-isomer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.1 There are no published studies of the pharmacological properties of 5-cis iloprost. | [References]
1. Schr?r, K., Darius, H., Matzky, R., et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) — equipotent to PGI2 in vitro Naunyn Schmiedebergs Arch. Pharmacol. 316(3),252-255(1981). |
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