| Identification | Back Directory | [Name]
1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE | [CAS]
82900-57-0 | [Synonyms]
BP 554
BP 554 MALEATE
1-[3-[(1,3-Benzodioxol-5-yl)oxy]propyl]-4-phenylpiperazine
Piperazine, 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenyl-
1-(3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)-4-phenylpiperazine
1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE | [Molecular Formula]
C20H24N2O3 | [MDL Number]
MFCD00209933 | [MOL File]
82900-57-0.mol | [Molecular Weight]
340.42 |
| Chemical Properties | Back Directory | [Boiling point ]
496.9±45.0 °C(Predicted) | [density ]
1.188±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
<45.65mg/ml in DMSO | [form ]
solid | [pka]
7.42±0.10(Predicted) | [color ]
Off-white |
| Hazard Information | Back Directory | [Uses]
BP 554 Maleate was used to study the methods for the classification and diagnosis of scoliosis. | [Definition]
ChEBI: 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenylpiperazine is a member of piperazines. | [Biological Activity]
Selective 5-HT 1A agonist. | [References]
[1]. matsuda t, seong yh, aono h, et al. agonist activity of a novel compound, 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenyl piperazine (bp-554), at central 5-ht1a receptors. eur j pharmacol, 1989, 170(1-2): 75-82.
[2]. galter d, unsicker k. sequential activation of the 5-ht1(a) serotonin receptor and trkb induces the serotonergic neuronal phenotype. mol cell neurosci, 2000, 15(5): 446-455.
[3]. rauch a, rainer g, logothetis nk. the effect of a serotonin-induced dissociation between spiking and perisynaptic activity on bold functional mri. proc natl acad sci u s a, 2008, 105(18): 6759-6764. |
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