| Identification | Back Directory | [Name]
1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- | [CAS]
831217-43-7 | [Synonyms]
116-9e
116 9e,1169e
116-9e, 10 mM in DMSO
116-9e >=98% (HPLC), powder
4-[1,1′-Biphenyl]-4-yl-3,4-dihydro-6-methyl-2-oxo-5-[(phenylmethoxy)carbonyl]-1(2H)-pyrimidinehexanoic acid
1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]-
6-(4-([1,1'-Biphenyl]-4-yl)-5-((benzyloxy)carbonyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)hexanoic acid
6-(4-([1,1'-biphenyl]-4-yl)-5-((benzyloxy)carbonyl)
-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)hexanoic acid | [Molecular Formula]
C31H32N2O5 | [MDL Number]
MFCD18632539 | [MOL File]
831217-43-7.mol | [Molecular Weight]
512.6 |
| Chemical Properties | Back Directory | [Boiling point ]
747.3±60.0 °C(Predicted) | [density ]
1.205±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: >20mg/mL | [form ]
powder | [pka]
4.76±0.10(Predicted) | [color ]
white to off-white |
| Hazard Information | Back Directory | [Uses]
116-9e has been used as an inhibitor of heat shock protein 70 (Hsp70) co-chaperone HDJ2 (human Ydj1/DNAJA1) to study the influence of HDJ2 on the regulation of ribonucleotide reductase (RNR) activity in HEK293 cells. It has also been used as an Hsp70 inhibitor to study the effect of Hsp70 chaperone on b5‐ops glycosylation in the side populations (SP) HeLa cells. | [Biochem/physiol Actions]
116-9e is a dihhydropyrimidine compound. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|