| Identification | Back Directory | [Name]
(3R,5R)-7-[1,2,6,7,8,8aβ-Hexahydro-8α-[[(2S)-2-methylbutyryl]oxy]-2β-methylnaphthalene-1β-yl]-3,5-dihydroxyheptanoic acid | [CAS]
84064-38-0 | [Synonyms]
Compactic acid
Mevastatin acid
(βR,δR,8aβ)-β,δ-Dihydroxy 2β-methyl-8α-[[(1S)-1-methylpropyl]carbonyloxy]decalin-3,4a(5)-diene-1β-heptanoic acid
(3R,5R)-7-[1,2,6,7,8,8aβ-Hexahydro-8α-[[(2S)-2-methylbutyryl]oxy]-2β-methylnaphthalene-1β-yl]-3,5-dihydroxyheptanoic acid
(3R,5R)-3,5-Dihydroxy-7-[[(1S)-1,2,6,7,8,8aβ-hexahydro-2β-methyl-8α-[[(2S)-2-methyl-1-oxobutyl]oxy]naphthalen]-1β-yl]heptanoic acid | [Molecular Formula]
C23H36O6 | [MOL File]
84064-38-0.mol | [Molecular Weight]
408.528 |
| Hazard Information | Back Directory | [Definition]
ChEBI:Mevinic acid is a member of the class of hexahydronaphthalenes that is 1,2,6,7,8,8a-hexahydronaphthalene which is substituted by a (3R,5R)-6-carboxy-3,5-dihydroxyhexyl group at position 1, a methyl group at position 2, and a (2S)-2-methylbutanoyloxy group at position 8 (the 1S,2S,8S,8aR isomer). Lactonisation of the hydroxy-carboxylic acid chain at position 1 affords mevastatin. It has a role as an EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor. It is a 3-hydroxy carboxylic acid, a member of hexahydronaphthalenes, a polyketide and a carboxylic ester. It is a conjugate acid of a mevinic acid anion. |
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