| Identification | Back Directory | [Name]
[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone | [CAS]
845614-11-1 | [Synonyms]
RG1678
RG1679
RO4917838
Bitopertin
Paliflutine
Palufidine,RG-1678
(S)-[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-(methanesulfonyl)-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]methanone
[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone
Methanone, [4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl][5-(methylsulfonyl)-2-[(1S)-2,2,2-trifluoro-1-methylethoxy]phenyl]- | [Molecular Formula]
C21H20F7N3O4S | [MDL Number]
MFCD18251496 | [MOL File]
845614-11-1.mol | [Molecular Weight]
543.46 |
| Chemical Properties | Back Directory | [Boiling point ]
635.1±55.0 °C(Predicted) | [density ]
1.444 | [storage temp. ]
Store at -20°C | [solubility ]
insoluble in H2O; ≥17.94 mg/mL in EtOH; ≥88.9 mg/mL in DMSO with ultrasonic | [form ]
crystalline solid | [pka]
3.57±0.39(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Bitopertin is a potent and noncompetitive glycine reuptake inhibitor (GRI). Bitopertin is an investigational agent for the treatment of schizophrenia. | [storage]
Store at -20°C |
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