| Identification | Back Directory | [Name]
5-Iodo-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | [CAS]
847551-49-9 | [Synonyms]
2-C-Me-7-deaza-7-iodo-A
5-Iodo-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
5-iodo-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
5-Iodo-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
4-Amino-5-iodo-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
4-Amino-5-iodo-7-(2-beta-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine | [Molecular Formula]
C12H15IN4O4 | [MDL Number]
MFCD17017898 | [MOL File]
847551-49-9.mol | [Molecular Weight]
406.176 |
| Chemical Properties | Back Directory | [Boiling point ]
675.7±55.0 °C(Predicted) | [density ]
2.28±0.1 g/cm3(Predicted) | [pka]
12.39±0.70(Predicted) | [InChI]
InChI=1/C12H15IN4O4/c1-12(20)8(19)6(3-18)21-11(12)17-2-5(13)7-9(14)15-4-16-10(7)17/h2,4,6,8,11,18-20H,3H2,1H3,(H2,14,15,16)/t6-,8-,11-,12-/s3 | [InChIKey]
VDPOJGOZLKLNFY-PMMCFNNLNA-N | [SMILES]
O1[C@H](CO)[C@@H](O)[C@@](C)(O)[C@@H]1N1C2=C(C(I)=C1)C(N)=NC=N2 |&1:1,4,6,9,r| |
| Hazard Information | Back Directory | [Uses]
5-Iodo-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (4-Amino-5-iodo-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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