ChemicalBook--->CAS DataBase List--->85031-59-0

85031-59-0

85031-59-0 Structure

85031-59-0 Structure
IdentificationBack Directory
[Name]

DihydroarteMisinic acid
[CAS]

85031-59-0
[Synonyms]

product/154911
Dihydroqinghao acid
Dihydroarteannuic acid
DihydroarteMisinic acid
Dihydro-Artmisinic Acid
(2R)-dihydroartemisinic acid
DihydroarteMisinic acid USP/EP/BP
1-Naphthaleneacetic acid, 1,2,3,4,4a,5,6,8a-octahydro-α,4,7-trimethyl-, (αR,1R,4R,4aS,8aS)-
2-(4,7-dimethyl-(1α-H),2,3,(4β-H),(4aα-H),5,6,(8aα-H)-octahydronaphthalen-1-yl)propionic acid
(alphaR,1R,4R,4aS,8aS)-1,2,3,4,4a,5,6,8a-Octahydro-alpha,4,7-trimethyl-1-naphthaleneacetic acid
[EINECS(EC#)]

813-723-9
[Molecular Formula]

C15H24O2
[MDL Number]

MFCD16876168
[MOL File]

85031-59-0.mol
[Molecular Weight]

236.35
Chemical PropertiesBack Directory
[Melting point ]

135-137°C
[Boiling point ]

358.8±11.0 °C(Predicted)
[density ]

0.999±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly), DMSO (Slightly)
[form ]

Solid
[pka]

4.65±0.10(Predicted)
[color ]

White to Off-White
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P
Hazard InformationBack Directory
[Uses]

Dihydroartemisinic Acid is produced and its content is increased in Artemisia annua when NAC transcription factor gene (AaNAC1) is overexpressed, which play an important role in response to various abiotic stresses. Also, it is related secondary metabolites of artemisinin which increases in A. annua under cold stress.
[Definition]

ChEBI: Dihydroartemisinic acid is a monocarboxylic acid that is propanoic acid substituted at position 2 by a (1S,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group. It is a sesquiterpenoid precursor of the antimalarial drug, artemisinin. It has a role as a plant metabolite. It is a carbobicyclic compound, a monocarboxylic acid, a member of octahydronaphthalenes and a sesquiterpenoid. It is a conjugate acid of a dihydroartemisinate.
Spectrum DetailBack Directory
[Spectrum Detail]

DihydroarteMisinic acid(85031-59-0)1HNMR
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