ChemicalBook--->CAS DataBase List--->851477-20-8

851477-20-8

851477-20-8 Structure

851477-20-8 Structure
IdentificationBack Directory
[Name]

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC)
[CAS]

851477-20-8
[Synonyms]

1-[3,5-Bis(trifluoroMethyl)phenyl]-3-[(1S,2S) -2-(diMethylaMino)cyclohexyl]thiourea
Thiourea, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(diMethylaMino)cyclohexyl]-
1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-2- (dimethylamino)cyclohexyl]thiourea,99%e.e.
1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC)
1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]
thiourea (S,S-TUC)
[Molecular Formula]

C17H21F6N3S
[MDL Number]

MFCD09834840
[MOL File]

851477-20-8.mol
[Molecular Weight]

413.428
Chemical PropertiesBack Directory
[Melting point ]

87-88°C
[alpha ]

+42° (c 1.16, CHCl3)
[Boiling point ]

380.8±52.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[form ]

Powder
[pka]

11.76±0.70(Predicted)
[color ]

white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Questions And AnswerBack Directory
[Reaction]

  1. Thiourea catalyst used in the enantio and diastereoselective Michael addition of malonates and ketoesters to nitroolefins.
  2. Catalyst used in the enantioselective hydrazination of 1,3-dicarbonyl compounds.
  3. Catalyst used for the dynamic resolution of azalactones.
  4. Catalyst used in Michael-Aldol reaction of 2-mercaptobenzaldehyde with α,β-unsaturated oxazolidinone.
  5. Catalyst for enantioselective synthesis of flavanones and chromanones.
  6. Catalyst for the asymmetric Neber Reaction.
  7. Catalyst for the three component synthesis of 2,6-diazabicyclo[2.2.2]octanones.
Reactions of 851477-20-8_1
Reactions of 851477-20-8_2
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